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Invitation: 16 September 16:00-17:00 iLab/UCP meeting
Sanne Booij - the iLab module

Hereby we invite you to the upcoming iLab meeting, where Sanne Booij will present the iLab module. The iLab module will systemically assess new patients with the aim to inform diagnostics and to establish a rich dataset to answer urgent scientific questions related to treatment outcomes, including risk for relapse. 

See more on the iLab module
information on the iLab website and the previous iLab newsletter, which was dedicated to the iLab module.

The Covid19 UMCG regulation only allows a limited number of persons in room 4.15. If you want to join the meeting in room 4.15, please send an e-mail to 
Precision medicine in mental health conference - 16 & 17 September 2021.
Get ready for two days of precision medicine in mental health where international experts will present their work and engage in panel discussions. The conference is hosted by Zachary Cohen (University of California, Los Angeles) and Wolfgang Lutz (Department of Clinical Psychology and Psychotherapy of the University of Trier).
Registration is possible until 13 September. Click here for more information.
EAPM young investigator award for Anne van Gils and Robin Groen
The European Association of Psychosomatic Medicine has granted the 2021 EAPM young investigator award to Anne van Gils and Robin Groen for their publication: "
Exploring temporal relationships among worrying, anxiety and somatic symptoms" which was published in Journal of Psychosomatic Research.
Congratulations for both!
Literature ambulatory assessments
For whom is interested: a research assistant of Prof Ebner-Priemer has kindly reviewed all literature in the last quarter of 2020 in Pubmed and Psychinfo on any articles about ambulatory assessement. The results can be found
Report of Symposium "Small is beautiful {again}"
By Marij Zuidersma

This conference about single-case experimental design (SCED) research was held online on 14, 15 and 16 April 2021. I made a detailed report of information that has been shared at this conference. It contains many references to interesting articles, guidelines, websites and shiny apps, and is also (particularly) interesting for those who would like to learn more about single-case experimental designs. 
Please click here for to access the document. (no access? send an e-mail to

Are you really interested in SCED? Join the world-wide SCED community at On their webpage you can share and find a lot of general information about SCED too.
Recent publications in the spotlight
Psychological networks as feedback in clinical practice? How valid and reliable are VAR-based networks?

By Laura Bringmann
I (yes, this time just me) wrote a short review on this (open access). 
I discuss the challenges and suggest some future paths! The future paths are:
1) using more sophisticated (VAR-based) network models, such as continuous-time VAR models or time-varying VAR models or models that include measurement error.
2) Actually checking the reliability of your network. For example, by using cross-validation, which provides information on whether the fitted VAR model is too complex for the available data. Or checking the predictability of the nodes.
3) Making the hypotheses of the network explicit.
4) Finally, another possible path is to step away from VAR-based networks completely. The network approach is not tied to a specific model, rather it generates hypotheses that should be tested with the models that are most suited.
So, the future of networks is bright and maybe or maybe not VAR based :-). Below, you can find the link to the paper. 

Laura F. Bringmann. Person-specific networks in psychopathology: past, present and future. Current Opinion in Psychology 2021: 41: 59-64.
Individual and common patterns in the order of symptom improvement during outpatient treatment for major depression

By Evelien Snippe 
In which order do depressive symptoms typically remit? Which depressive symptoms improve first when patients receive treatment? This paper combined an idiographic and nomothetic approach to these study these questions. The timing of improvement was determined for each symptom in each individual using weekly depressive symptom data over the course of treatment. Which symptoms improved first differed markedly across patients. The core depression symptoms sad mood and loss of interest/pleasure  improved 1.5 to 2 times more often before than after symptoms of anxiety, negative cognitions, and energy.

Snippe E, Doornbos B, Schoevers RA, Wardenaar KJ, Wichers M. J Affect Disord. 2021 May 2;290:81-88. doi: 10.1016/j.jad.2021.04.097.
New projects

Lifestyle study LEEF
Project group: Edith Liemburg, Danielle Cath, Shamira Kuiper, Maartje Hofman, Jolien Kik, Tryntsje Fokkema, Jolien Panjer

By Edith Liemburg

In 2019 a study on a lifestyle intervention called LEEF has started at mental health service (GGZ) Drenthe. This is a combined lifestyle intervention for individuals with depressive and mood symptoms. This study has some new elements compared to previous studies, including use of buddies (from the social network of the patient), addition of cooking skills and positive psychology, and activity tracking by using a Fitbit (Charge 4). The Fitbit is being used as an intervention tool to stimulate participants to get more active. To measure the effectiveness of the intervention, the level of activity will be measured before, during and after the intervention using MotionWatches of the iLab. A control group in the waiting list condition will be carrying a MotionWatch as similar time points. In the pilot phase of the study we will compare information acquired from the Fitbit to that of the MotionWatch.

Interesting courses
To be announced: ESM Data Analysis course Maastricht University by Wolfgang Viechtbauer

9-11 March 2022: REAL ESM/EMA workshop KU Leuven live in Leuven, so not online!

Online courses:
- search
Coursera for an online course to your interest. They have numerous statistical/methodological or content-related online courses.
- Learn R through Datacamp. The iLab has a subscription for DataCamp. Send an e-mail to if you are interested.
ARIMA and VAR analysis by Elske Bos (send an e-mail to if you are interested but have no access to the google drive)
Upcoming symposia, conferences
Recent publications
Folkersma W, Veerman V, Ornée DA, Oldehinkel AJ, Alma MA, Bastiaansen JA. Patients' experience of an ecological momentary intervention involving self-monitoring and personalized feedback for depression. Internet Interv. 2021 Jul 19;26:100436. doi: 10.1016/j.invent.2021.100436. eCollection 2021 Dec.
Harnas SJ, Knoop H, Booij SH, Braamse AMJ. Personalizing cognitive behavioral therapy for cancer-related fatigue using ecological momentary assessments followed by automated individual time series analyses: A case report series. Internet Interv. 2021 Jul 14;25:100430. doi: 10.1016/j.invent.2021.100430. eCollection 2021 Sep.
George SV, Kunkels YK, Booij S, Wichers M. Uncovering complexity details in actigraphy patterns to differentiate the depressed from the non-depressed. Sci Rep. 2021 Jun 29;11(1):13447. doi: 10.1038/s41598-021-92890-w.
Wijbenga RA, Blaauw FJ, Janus SIM, Tibben C, Smits AE, Oude Voshaar RC, Zuidema SU, Zuidersma M. Individual differences in the temporal relationship between sleep and agitation: a single-subject study in nursing home residents with dementia experiencing sleep disturbance and agitation. Aging Ment Health. 2021 Jun 15:1-9. doi: 10.1080/13607863.2021.1935464. 
Kunkels YK, Riese H, Knapen SE, Riemersma-van der Lek RF, George SV, van Roon AM, Schoevers RA, Wichers M. Efficacy of early warning signals and spectral periodicity for predicting transitions in bipolar patients: An actigraphy studyTransl Psychiatry. 2021 Jun 7;11(1):350. doi: 10.1038/s41398-021-01465-w.
Thunnissen MR, Aan Het Rot M, van den Hoofdakker BJ, Nauta MH. Youth Psychopathology in Daily Life: Systematically Reviewed Characteristics and Potentials of Ecological Momentary Assessment Applications. Child Psychiatry Hum Dev. 2021 Jun 1. doi: 10.1007/s10578-021-01177-8. 
Schmitter M, van Roekel E, Heininga VE, Oldehinkel AJ. Personalized lifestyle advice alters affective reactivity to negative events in anhedonic young adults. J Affect Disord. 2021 Aug 1;291:118-125. doi: 10.1016/j.jad.2021.04.036. 
Castro-Alvarez S, Tendeiro JN, Meijer RR, Bringmann LF. Using structural equation modeling to study traits and states in intensive longitudinal data. Psychol Methods. 2021 May 20. doi: 10.1037/met0000393. 
Minaeva O, George SV, Kuranova A, Jacobs N, Thiery E, Derom C, Wichers M, Riese H, Booij SH. Overnight affective dynamics and sleep characteristics as predictors of depression and its development in women. Sleep. 2021 May 20:zsab129. doi: 10.1093/sleep/zsab129.
Snippe E, Doornbos B, Schoevers RA, Wardenaar KJ, Wichers M. Individual and common patterns in the order of symptom improvement during outpatient treatment for major depression. J Affect Disord. 2021 Jul 1;290:81-88. doi: 10.1016/j.jad.2021.04.097. 
Bringmann LF. Person-specific networks in psychopathology: Past, present, and future. Curr Opin Psychol. 2021 Mar 19;41:59-64. doi: 10.1016/j.copsyc.2021.03.004.
iLab website 
iLab staff
Harriëtte Riese: (head of iLab)
Gerda Bloem: (equipment and room reservations)
Klaas Wardenaar: (statistical advice, newsletters)
Marij Zuidersma: (newsletters and iLab website)
Robert Schoevers: (head of UCP) 
Sanne Booij: (iLab module)

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