i-CASE

Idiographic study of Cognitive function, Affect, and Sleep in the Elderly

Purpose of the study

Evaluate the temporal dynamics between sleep disturbances, depression and cognitive function within elderly individuals with cognitive impairments and depression.
Evaluate whether other (time-varying and time-stable) variables, such as the circadian rhythm, the presence of somatic diseases and physical activity affect the temporal relationship between sleep disturbances, depression and cognitive function within the individual
Evaluate whether giving feedback on personal triggers for cognitive impairments, depression and sleep disturbances to patients gives insight to these patients and is helpful for them

Researchers

Date

2014-02-01

- 2019-06-30

Participants

20 Patients with mild cognitive impairments of mild dementia due to Alzheimer’s disease, and with depression (according to MINI or GDS>=4).

Publications

Zuidersma et al., 2022b

Feasibility, usability and clinical value of intensive longitudinal diary assessments in older persons with cognitive impairment and depressive symptoms

Zuidersma et al 2022a

Temporal dynamics of depression, cognitive performance and sleep in older persons with depressive symptoms and cognitive impairments: a series of eight single-subject studies

Zdanowski et al 2022

Intra-Individual Variability in Cognitive Performance Can Befuddle the Study of Cognitive Impairments and Decline

Zuidersma et al 2022b