Finished projects that used iLab facilities
Study | Experience sampling feedback in the diagnosis of first psychosis |
Investigators | Drs. F.M. Bos, Dr. W.A. Veling, Dr. E. Snippe, Dr. J.A.J. van der Krieke, Prof. Dr. M.C. Wichers, Dr. R. Bruggeman |
Date | Sept 2017 onwards |
Purpose | To investigate the application of experience sampling methodology (ESM) feedback to the diagnosis of patients with first psychosis. We will evaluate 1) what insights ESM feedback offers patients and clinicians, and 2) in what way ESM feedback influences ensuing treatment. |
Participants | 20 patients with first psychosis |
Study | Sleep and agitation in nursing home patients with dementia |
Investigators | Prof. Dr. S.U. Zuidema, Drs. R. Wijbenga, Dr. M. Zuidersma |
Date | February 2017- July 2017 |
Purpose | The aim is to investigate the temporal association between sleep and agitation in nursing home residents with dementia. Do temporal associations between sleep and agitation differ between individuals? And what is the feasibility of evaluating sleep and agitation with actigraphy for 2 months in dementia patients? |
Participants | 5 nursing home residents with dementia |
Study | SWITCH-BD: Sleep-wake patterns in the change of mood in bipolar disorder. |
Investigators | Prof. dr. R.A. Schoevers, dr. R.F. Riemersma-van der Lek, S.E. Knapen, MSc |
Date | September 2016 – November 2017 |
Purpose | The SWITCH-BD study aims to unravel the relationship between circadian rhythm disturbances, sleep problems and the development of mood episodes in patients with bipolar disorder. |
Participants | Patients with bipolar disorder type I |
Study | Pilot TRANS-ID tapering: transitions in depressive symptoms during tapering of antidepressants |
Investigators | Prof. M. Wichers & Dr. E. Snippe |
Date | Nov 2015 – Jan 2017 |
Purpose | The aim of this pilot study is to examine (1) whether monitoring of daily experiences during and after tapering of antidepressants gives personalized insights in warning signals preceding transitions in depression (2) whether individuals find it helpful to monitor their daily experiences during and after tapering of depressive symptoms. Furthermore, the feasibility of this intensive diary study will be examined and the diary questions included in the study will be evaluated with participants. This is a pilot for the larger TRANS-ID tapering study. |
Participants | Participants should meet all of the following criteria: – age ≥ 18 – a history of depressive symptoms – having made a shared decision with a mental health care provider to taper the current dose of antidepressant medication – having made a tapering scheme or plan with a mental health care provider |
Study | The effect of Virtual Reality exposure Therapy (VRET) on social participation in people with a psychotic disorder: a multisite randomised controlled trial |
Investigators | Chris Geraets, msc Drs. Roos Pot-Kolder (VU) Dr. Wim Veling Prof. Dr. Mark vd Gaag |
Date | Nov 2014 – Dec 2015 |
Purpose | First, to investigate the effect of Virtual Reality exposure therapy on social participation. Second, to investigate the longitudinal course of symptoms and social behaviour in psychosis on group and individual level. |
Participants | 100 patients with psychotic disorder |
Study | Idiographic study of Cognitive function, Affect, and Sleep in Early Alzheimer (i-CASE) |
Investigators | Dr. Marij Zuidersma, Prof. Richard Oude Voshaar |
Date | February 2014 – June 2019 |
Purpose | 1) Evaluate the temporal dynamics between sleep disturbances, depression and cognitive function within elderly individuals with cognitive impairments and depression.2) Evaluate whether other (time-varying and time-stable) variables, such as the circadian rhythm, the presence of somatic diseases and physical activity affect the temporal relationship between sleep disturbances, depression and cognitive function within the individual3) Evaluate whether giving feedback on personal triggers for cognitive impairments, depression and sleep disturbances to patients gives insight to these patients and is helpful for them |
Participants | 20 Patients with mild cognitive impairments of mild dementia due to Alzheimer’s disease, and with depression (according to MINI or GDS>=4). |
Study | NESDA diary study |
Investigators | Dr H. Riese, Prof Dr R.A. Schoevers, Dr F. Lamers, Dr L. Boschloo, Prof Dr P. de Jonge |
Date | 2014 – 2017 |
Purpose | The main aim of this study is to provide new insights into the nature of daily mood fluctuations that can explain the differences in severity and nature of mood disorder beyond the traditional DSM classifications. |
Participants | 400 patients with mood disorders, their sibs and healthy controls |
Study | Simvastatine-study |
Investigators | Prof. Dr. I.E.C. Sommer, Prof. W. Veling, Prof. R. Bruggeman, Dr. M. Begemann, Dr. S Schuite-Koops, S.Gangadin, M. Bak, E. van ’t Hag |
Date | September 2013 – December 2019 |
Purpose | To evaluate whether simvastatin addition improves symptoms, cognition, metabolic syndrome and movement disorders in patients with recent-onset psychotic disorder. |
Participants | 121 patients with psychotic disorder |
Study | TRENSS 2 |
Investigators | Drs. C. Kos, Prof. Dr. A. Aleman |
Date | September 2012- May 2018 |
Purpose | The main objective is to investigate whether treatment using neurostimulation (tDCS or rTMS) targeting the rDLPFC reduces apathy in schizophrenia patients by activating the targeted brain region and whether tDCS is equally effective as rTMS. A secondary aim is to evaluate if a psychosocial intervention, in the form of BAT, in addition to a biological intervention, TMS, further reduces the level of apathy. |
Participants | 125 schizophrenia patients |
Study | Blues Clues |
Investigators | Dr. M. aan het Rot, K. Hogenelst, M.Sc., Prof. Dr. R.A. Schoevers |
Date | April 2012 – August 2014 |
Purpose | To investigate the role of serotonin in mood and interactions with others |
Participants | 60 individuals with a family history of depression |
Website | www.bluesclues.nl |
Study | Trichotillomanics |
Investigators | S.D.M. van Dijk, Dr. E.H. Bos |
Date | February 2012 |
Purpose | To investigate the usefulness of the Psymate as an intervention tool in Trichotillomanics |
Participants | 1 patient with trichotillomanics |
Study | No Fun No Glory |
Investigators | Prof. Tineke Oldehinkel, Dr. Eeske van Roekel, Dr. Charlotte Vrijen, Drs. Vera Heininga, Drs. Maurits Masselink |
Date | 2015-2016 |
Purpose | This exploratory intervention study is set out to examine effects of tailor-made lifestyle advice, based on observed individual temporal patterns of lifestyle factors and experienced pleasure, as a non-pharmacological means to restore the pleasure of everyday activities and accomplishments. In addition, we will explore whether exposure to tandem skydiving, an experience known to activate the dopamine system and to elicit strong emotions, can help to reboot the reward system and hence foster the recommended lifestyle changes. |
Participants | N = 69 anhedonic participants, N = 69 healthy controls |
Study | Stress hormone dynamics in healthy individuals |
Investigators | S.L. van Ockenburg, MD, Prof. Dr. J.G.M Rosmalen |
Date | July 2012-March 2013 |
Purpose | The objective of this study is to investigate the within-person dynamics of psychosocial stress levels and its effect on subsequent day-to-day fluctuations in blood pressure, heart rate, cortisol and melatonin levels in healthy volunteers for a period of 63 consecutive days by means of multivariate time-series analyses. |
Participants | 10 healthy volunteers |
Study | Uncovering the Positive Potential of Emotional Reactivity (UPPER): A combined diary-neuroimaging approach |
Investigators | Dr. J.A.C.J. Bastiaansen, Drs. E.C. Bennik, Prof. dr. A.J. Oldehinkel, Prof. dr. J. Ormel NIC: Prof. Dr. A. Aleman and Dr. J.B.C. Marsman |
Date | June 2012 –December 2013 |
Purpose | The proposed study aims to investigate whether (part of the) individuals who are at high risk to develop affective problems when faced with adversities also benefit more from positive environmental influences. Its main objective is to investigate how emotional reactivity to negative experiences and emotional reactivity to positive experiences are related in daily life and in the brain. |
Participants | 75 healthy students |
Study | Mood and Movement in Daily life (MOOVD) |
Investigators | S.H. Booij, MSc, M.E.J. Bouwmans, MSc, Dr. E.H. Bos, Prof. dr. P. de Jonge, Prof. dr. A.J. Oldehinkel |
Date | 2012 – June 2014 |
Purpose | The primary aim of this study is to investigate the role of physical activity in the etiology of depressed mood, individual differences therein, and clues for tailor-made interventions. A second aim of this study is to elucidate the temporal relationship between mood symptoms and several stress-related hormones and enzymes, such as cortisol and alpha-amylase. |
Participants | 60 (30 depressed individuals, 30 non-depressed individuals) |
Study | Fluctuations in Agoraphobia |
Investigators | S.A. Nijdam, BSc, Dr. H. Riese, Prof. Dr. R.A. Schoevers |
Date | Oct 2012 – Mar 2013 |
Purpose | Investigating the bidirectional association between heart rate variability (HRV) and anxiety symptoms to get a better understanding of the individual etiology of patients with panic disorder combined with agoraphobia. |
Participants | 3 patients with agoraphobia |